THE LDN-27219 BIOACTIVITY DIARIES

One significantly appealing compound is LDN-27219. Even though most tTG inhibitors are intended to bind for the protein crosslinking Lively website, LDN-27219 instead binds into the nucleotide binding pocket with the enzyme although it is in its shut-point out conformation, and stabilizes that conformation to prevent crosslinking activity.78 Schnei